What is extranodal lymphoma?
What is extranodal lymphoma?
The term extranodal disease refers to lymphomatous infiltration of anatomic sites other than the lymph nodes. Almost any organ can be affected by lymphoma, with the most common extranodal sites of involvement being the stomach, spleen, Waldeyer ring, central nervous system, lung, bone, and skin.
What do lymphoma lesions look like?
The lesions are often itchy, scaly, and red to purple. The lymphoma might show up as more than one type of lesion and on different parts of the skin (often in areas not exposed to the sun). Some skin lymphomas appear as a rash over some or most of the body (known as erythroderma).
Which of the following is the most common site for extranodal lymphoma?
The most frequently involved system is GI tract (Stomach being the commonest site) followed by Waldeyer’s ring (when tonsil is considered as an extranodal site), lung, liver, spleen, bone and and skin (1).
Is extranodal lymphoma treatable?
A combined treatment with chemotherapy and RT is considered a valid therapeutic approach in patients with localized NHL, either nodal or extranodal, in most anatomic sites, including Waldeyer’s ring (100-102). However, the combinatory treatment is often associated with relevant acute and chronic toxicity (99,103).
What causes extranodal lymphoma?
Extranodal NK/T-cell lymphoma, nasal type, is strongly linked to infection with a virus called Epstein-Barr virus (EBV). EBV is a very common virus that can cause glandular fever. After you’ve been infected with it, EBV stays in your body but it is normally kept under control by your immune system.
How common is extranodal lymphoma?
Extranodal involvement can be seen with lymphoma in approximately 25–40% of cases and almost any organ can be involved[2,3]. Extranodal involvement is less common with Hodgkin disease (HD) with direct extension into adjacent organs in 15% and hematogenous spread in 5–10%.
What does extranodal mean?
Definition: Primary Extranodal Lymphoma. When lymphoma is believed to have originated outside the lymph nodes, it’s called extranodal lymphoma, or more precisely, primary extranodal lymphoma. At times, it can be difficult to pinpoint where in the body a lymphoma began.
What is NK T-cell lymphoma?
NK T-cell lymphoma is an aggressive type of cancer that attacks the natural killer cells and/or T-cells used by the immune system to fight viruses, bacteria, and tumor cells. This disease is also known as nasal type NK lymphoma, anglocentric lymphoma, or extranodal natural killer cell lymphoma.
What is solid organ lymphoma?
Lymphoma (lymposarcoma) in animals is a type of cancer defined by a proliferation of malignant lymphocytes within solid organs such as the lymph nodes, bone marrow, liver and spleen. The disease also may occur in the eye, skin, and gastrointestinal tract.