What is indole used for?

What is indole used for?

Indole-3-carbinol is used for prevention of breast cancer, colon cancer, and other types of cancer. The National Institutes of Health (NIH) has reviewed indole-3-carbinol as a possible cancer preventive agent and is now sponsoring clinical research for breast cancer prevention.

What foods contain indole?

Indole-3-carbinol is formed from a substance called glucobrassicin found in vegetables such as broccoli, Brussels sprouts, cabbage, collards, cauliflower, kale, mustard greens, turnips, and rutabagas.

What is Meta I3C used for?

Benefits: Helps support the health of estrogen-sensitive tissues* Helps to promote the formation of “good,” protective 2-OH via its influence on hydroxylation pathways* Supports the detoxification of estrogens, and may also support healthy metabolism of other steroid hormones and xenoestrogens*

Can indole-3-carbinol help lose weight?

These findings suggest that I3C has a potential benefit in preventing obesity and metabolic disorders, and the action for I3C in vivo may involve multiple mechanisms including decreased adipogenesis and inflammation, along with activated thermogenesis.

Is indole toxic?

Indole, a derivative of the amino acid tryptophan, is a toxic signaling molecule, which can inhibit bacterial growth. To overcome indole-induced toxicity, many bacteria have developed enzymatic defense systems to convert indole to non-toxic, water-insoluble indigo.

Where is indole found?

coal tar
Indole is a solid at room temperature. It occurs naturally in human feces and has an intense fecal odor. At very low concentrations, however, it has a flowery smell, and is a constituent of many perfumes. It also occurs in coal tar.

Can indole 3 carbinol raise blood pressure?

Results: Cyp1a1-Ren2 rats induced with I3C exhibited pronounced increases in systolic blood pressure (SBP) (132 +/- 3-229 +/- 11 mm Hg, P < 0.001) and marked decreases in body weight (303 +/- 4-222 +/- 2 g, P < 0.001).

What is the difference between dim and indole 3 carbinol?

DIM is formed naturally when I3C is broken down in the gut. Unlike I3C, there are no published human studies on DIM. In fact, there are few published studies at all….ANTI-CANCER EFFECTS OF I3C.

Inhibits Growth of Estrogen Receptor Positive Breast Cancer Cells

What is the difference between I2C and I3C?

I3C is more power efficient than I2C, even while servicing I2C devices. I3C also reduced energy consumption while providing higher data rates at 12.5 MHz versus the 400 kHz of I2C. All of these improvements will be experienced with I3C while maintaining full compatibility with legacy I2C devices.

Does indole 3 carbinol increase testosterone?

According to our results, several steroid hormones (estradiol, estrone sulphate and androstenedione) were significantly increased in I3C treated tumor homogenates while testosterone was diminished. Interestingly, testosterone was significantly increased in the sera of I3C treated mice.

Is melatonin an indole?

Melatonin consists of an indole core bearing an N-acetyl-2-aminoethyl chain at C3 and a methoxy group linked to C5 (Scheme 1).

What is the systematic name for indole?


Preferred IUPAC name 1H-Indole
Other names 2,3-Benzopyrrole, ketole, 1-benzazole
CAS Number 120-72-9

Which is the best tablet for a child?

The Amazon Fire Kids tablet can run as a handy kids tablet, but it takes a bit of setup to get ready for that purpose. If you don’t take those steps, it’d be as capable a tablet as any other Fire tablet that an adult might use. The LeapFrog Epic tablet is a more focused device for your child’s education.

What’s the price of a Fire tablet for kids?

The 8-inch Kids model (based on the standard Fire HD 8 above) costs $139.99 right now, which is worth the increase in price over the regular model if you think there’s a possibility for breakage. Amazon’s tablets have a simplified interface, strong parental controls, and Kids+, which is basically a giant bucket of content for kids.

Which is the best iPad for a child?

The iPad Mini is an ideal alternative, offering most of the iPad benefits with a smaller 7.9-inch display that’s more comfortable for kids. The 64GB model is fine for children’s use and helps keep the price down, especially compared to the latest standard iPads.

Why is it important for kids to have a tablet?

The newest kids’ tablets not only provide portable entertainment, they also give your child the chance to learn new things while on the go with a variety of educational apps and games. You’ll also want to be sure to choose a device that is compatible with the software you want to access.